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What is the mechanism of action of Sildalist 120 mg?

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    42256316
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    Sildalist 120 mg contains two active ingredients: sildenafil citrate (100 mg) and tadalafil (20 mg). Both sildenafil and tadalafil belong to a class of medications called phosphodiesterase type 5 (PDE5) inhibitors. Here’s how they work:

    Cenforce 200 mg: Sildenafil works by inhibiting the enzyme phosphodiesterase type 5 (PDE5). When a man is sexually stimulated, nitric oxide is released in the erectile tissue of the penis. Nitric oxide activates the enzyme guanylate cyclase, which increases levels of cyclic guanosine monophosphate (cGMP). This results in relaxation of the smooth muscles in the penile blood vessels, allowing for increased blood flow to the penis and an erection. By inhibiting PDE5, sildenafil helps to maintain higher levels of cGMP, prolonging the vasodilatory effects and enhancing erectile function.

    Vidalista 40 mg: Tadalafil also works by inhibiting PDE5, but it has a longer duration of action compared to sildenafil. Additionally, tadalafil has another mechanism of action that involves inhibiting the enzyme phosphodiesterase type 11 (PDE11). By inhibiting PDE11, tadalafil may have additional effects on smooth muscle relaxation and vasodilation in various tissues throughout the body.

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